'Brazen, Targeted Attack': UnitedHealthcare CEO Fatally Shot Outside Hotel in Manhattan Brian Thompson was killed in what the NYPD says was a targeted attack.

Brian Thompson, 50, the CEO of UnitedHealthcare was fatally shot Wednesday morning in Midtown Manhattan.

Thompson was arriving at the Hilton hotel around 6:46 a.m. for UnitedHealth Group's Investor Day, which was being held in the ballroom, where a masked man waiting for him.

"It appears the suspect was lying in wait for several minutes and as the victim was walking to the conference hotel, the suspect approached from behind and fired several rounds, striking the victim at least once in the back and at least once in the right calf," NYPD Commissioner Jessica Tisch said in a Wednesday statement.

Thompson was taken to a local hospital before being pronounced dead.

"The shooter steps onto the sidewalk from behind the car, he ignores numerous other pedestrians, approaches the victim from behind and shoots him in the back," said NYPD Chief of Detectives Joseph Kenny at the press conference. "The shooter then walks toward the victim and continues to shoot."

"From watching the video, it does seem like he is proficient in the use of firearms," Kenny added.

UnitedHealth Group canceled the Investor Day event.

"I'm afraid that we – some of you may know we're dealing with very serious medical situation with one of our team members," UnitedHealth Group staff said during the investor day, according to a transcript, per CNBC. "And as a result, I'm afraid we're going to have to bring to a close the event today, which I'm sure you'll understand."

Thompson was named CEO in April 2021. UnitedHealth Group, which is UnitedHealthcare's parent company, is No. 5 in the Fortune 500.

The investigation is ongoing and no arrests have been made, per the NYPD.

"We will not [rest] until we identify and apprehend the shooter in this case," Tisch said.

This is a breaking news story and will be updated.