Innovation Nation 50 cities and 10 lifestyles energizing businesses of all shapes and sizes.

Whatever your entrepreneurial aspirations, there's a city to match your needs, accelerate your company's growth and improve your quality of life. Which is the one for you? Entrepreneur identifies 50 cities and 10 lifestyles energizing businesses of all shapes and sizes.

Even in harsh economic times, America is still the land of opportunity, especially for entrepreneurs with the vision, ambition and flexibility to follow that opportunity wherever it may lead. In an increasingly connected world, no longer are businesses or their owners tethered to one spot on the map: Whether you're sizing up a regional opportunity, looking for a change of scenery or simply desiring a certain lifestyle, there's a location and culture that's perfect for you.

The challenge is identifying which spot is the best fit. Entrepreneur selected 10 contemporary American lifestyles and 50 related cities to complement all kinds of business types. Whether you're looking for tropical breezes, crisp mountain air, crowded city streets or wide, open spaces, they're all here.

Our methodology is as far-ranging as the list itself, incorporating statistical data, lifestyle studies and empirical research. Some choices may seem to be no-brainers, others may surprise you, and still others may have you reconsidering segments of the U.S. in a whole new light. That's the essence of American business: The only constant is change.